Jane A Grasby Selected Research

Flap Endonucleases

12/2018	Flap Endonuclease 1 Mutations A159V and E160D Cause Genomic Instability by Slowing Reaction on Double-Flap Substrates.
1/2017	Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability.
1/2017	Corrigendum: Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability.
4/2010	Substrate recognition and catalysis by flap endonucleases and related enzymes.

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Jane A Grasby Research Topics

Disease

3	Genomic Instability 12/2018 - 01/2017
1	Neoplasms (Cancer) 01/2017
1	Complementation Group G Xeroderma Pigmentosum 04/2010
1	Acquired Immunodeficiency Syndrome (AIDS) 07/2002

Drug/Important Bio-Agent (IBA)

4	Flap EndonucleasesIBA 12/2018 - 04/2010
2	EnzymesIBA 01/2017 - 04/2010
2	Phosphates (Orthophosphate)IBA 01/2017 - 01/2017
1	MetalsIBA 04/2010
1	DNA (Deoxyribonucleic Acid)IBA 04/2010
1	EndonucleasesIBA 04/2010
1	Nucleic AcidsIBA 04/2010
1	Tyrosine (L-Tyrosine)FDA Link 07/2002
1	T5 D15 exonucleaseIBA 07/2002